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Epigenetic marks imply a common cellular origin of virus- and UV-associated Merkel cell carcinoma (MCC). Epigenetic marks imply a common cellular origin of virus- and UV-associated Merkel cell carcinoma (MCC)

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NIAID Data Ecosystem2026-03-12 收录
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Differences in DNA-methylation between VP- and UV-MCCs mainly refer to heterogeneity in carcinogenesis rather than an origin in utterly different cell types. Indeed, a principal component derived scoring suggest an epithelial for UV-MCC as well as VP-MCC cell lines. Overall design: This study compared the DNA methylation patterns of virus- (VP-MCC) and UV-light associated (UV-MCC) Merkel cell carcinoma cell lines

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2021-06-14
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