Physiologically-based Pharmacokinetic (PBPK) model of estradiol disposition in humans. Based on Sier et al_2017_estrogen PBPK_simple (MODEL1711210001), but with intrinsic (i.e. liver-mediated) clearan
Accompanying OMEX file for the Physiome article "Reproducibility Study on a PBPK Model of FcRn-Mediated Recycling for Large Molecules".An OMEX archive is the Open Modelling Exchange format, the techni
Numerous studies have engineered nanoparticles with different physicochemical properties to enhance the delivery efficiency to solid tumors, yet the mean and median delivery efficiencies are only 1.48
aAll the parameters are defined in the Appendix S1 with the usual nomenclature: Vmax representing the maximum velocity rate of metabolism, Km the Michaelis-Menten affinity rate constant, VAT the adipo
