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Cell Therapy for Hirschsprung Disease-Associated Enterocolitis: Evaluation of the Effects and Safety of Mesenchymal Stem Cells on Intestinal Macrophages

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NIAID Data Ecosystem2026-03-14 收录
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MSCs were transplanted into HAEC mice for therapeutic purposes. Our data showed that MSCs could ameliorate HAEC symptoms by promoting M1-to-M2 phenotype polarization via COX-2 mediated MAPK/ERK signaling pathway, thus providing novel insights and potentially promising strategy for the treatment or prevention of HAEC.

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2023-03-27
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