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Transcription profiling of mouse lymphoma L5178Y cells treated with Cisplatin - ILSI-HESI Genotoxicity Study - Cisplatin

ChEBI2004-02-13 更新2026-07-21 收录

药物遗传毒性评估

癌症化疗机制研究

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-TOXM-4 数据链接链接失效反馈

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资源简介：

Transcription profiling of mouse lymphoma L5178Y cells treated with Cisplatin - ILSI-HESI Genotoxicity Study - Cisplatin

应用场景：

创建时间：

2004-02-13

药物遗传毒性评估

癌症风险生物标志物

Genome instability is a hallmark of most human cancers and is exacerbated following cellular exposure to exogenous/endogenous chemicals that can promote replication stress, activation of low-fidelity

NIAID Data Ecosystem40

Evaluation of anticytotoxic and antigenotoxic activities in the bone marrow of mice treated with sulfonamide chalcone N-{4-[3-(4-nitrophenyl)prop-2-enoyl]phenyl}-benzenesulfonamide (CPN) plus mitomycin C (MMC) based on MNPCE and PCE/NCE frequency.

药物遗传毒性评估

小鼠骨髓

1 Negative control: dimethylsulfoxide (DMSO) 0.1 mL/10 g body weight (b.w.) 2 Positive control: mitomycin C (MMC) 4 mg/kg (80% LD50). All values are mean ± SD of five mice. 3 Statistical analysis: one

NIAID Data Ecosystem10

Genotoxic alterations of cord blood cells in newborns exposed in utero to a zidovudine-based antiretroviral combination

母婴HIV治疗安全性

药物遗传毒性评估

Genotoxic alterations of cord blood cells in newborns exposed in utero to a zidovudine-based antiretroviral combination

ChEBI2012-05-02 更新10

Number of breaks per cell in cultured lymphocytes from FA patients.

染色体断裂

药物遗传毒性评估

The effect of the Vorinostat was calculated by the percentage of reduction of the number of breaks per cell in the Vorinostat treatments relatively to Spontaneous breaks and DEB. Number of breaks per

NIAID Data Ecosystem30

Markers of genomic damage in HIV-uninfected children exposed to zidovudine in utero. Markers of genomic damage in HIV-uninfected children exposed to zidovudine in utero

药物遗传毒性评估

围产期药物暴露监测

Zidovudine (ZDV) is a nucleoside reverse transcriptase inhibitor (NRTI) which competitively inhibits HIV reverse transcriptase and is incorporated into the viral DNA, resulting in DNA chain terminatio

NIAID Data Ecosystem10

Transcription profiling of mouse lymphoma L5178Y cells treated with Cisplatin - ILSI-HESI Genotoxicity Study - Cisplatin

资源简介：

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