RNA-seq reveals that Air1 and Air2 control TRAMP substrate specificity for nuclear RNA surveillance

ChEBI2012-11-14 更新2026-07-21 收录

RNA监视机制

TRAMP复合物功能

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-42231 数据链接链接失效反馈

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RNA-seq reveals that Air1 and Air2 control TRAMP substrate specificity for nuclear RNA surveillance

创建时间：

2012-11-14

Substrate Specificity of the TRAMP Nuclear Surveillance Complexes

RNA监视机制

转录后调控

During nuclear surveillance, the RNA exosome functions together with the TRAMP complexes, which include the RNA helicase Mtr4 together with a RNA binding protein (Air1 or Air2) and a poly(A) polymeras

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Data_Sheet_1_A Two-Headed Monster to Avert Disaster: HBS1/SKI7 Is Alternatively Spliced to Build Eukaryotic RNA Surveillance Complexes.FASTA

RNA监视机制

植物可变剪接调控

The cytosolic RNA exosome, a 3′→5′ exoribonuclease complex, contributes to mRNA degradation in eukaryotes, limiting the accumulation of poorly-translated, improperly translated, or aberrant mRNA speci

NIAID Data Ecosystem30

Certain Adenylated Non-Coding RNAs, Including 5′ Leader Sequences of Primary MicroRNA Transcripts, Accumulate in Mouse Cells following Depletion of the RNA Helicase MTR4

RNA监视机制

MicroRNA调控

RNA surveillance plays an important role in posttranscriptional regulation. Seminal work in this field has largely focused on yeast as a model system, whereas exploration of RNA surveillance in mammal

NIAID Data Ecosystem20

Mechanistic insights into the role of the canonical poly(A) polymerase Pla1 in RNA surveillance by the fission yeast MTREC complex

RNA监视机制

表观遗传调控

In this study we analysed the functional relevance of the interaction between Pla1 and the MTREC complex core component Red1 using various high throughput sequencing analyses performed on different Pl

NIAID Data Ecosystem30

Oncogenic CDK13 Mutations Impede Nuclear RNA Surveillance [humanRibominusRNAseq]. Oncogenic CDK13 Mutations Impede Nuclear RNA Surveillance [humanRibominusRNAseq]

RNA监视机制

CDK13突变致癌

RNA surveillance pathways detect and degrade defective transcripts to ensure RNA fidelity. We find disrupted nuclear RNA surveillance is oncogenic. Cyclin Dependent Kinase 13 (CDK13) is mutated in mel

NIAID Data Ecosystem30

RNA-seq reveals that Air1 and Air2 control TRAMP substrate specificity for nuclear RNA surveillance

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