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Expression data from mouse optic nerve and optic tract. Expression data from mouse optic nerve and optic tract

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NIAID Data Ecosystem2026-03-10 收录
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A membrane protein SIRPα (CD172a) interacts with another membrane protein CD47 and thereby constitutes a cell–cell contact signal. To investigate the functional role of CD47-SIRPα signal in the brain, we analyzed the effect of genetic ablation of CD47-SIRPα signal on the gene expression profile in specific brain regions by the use of microarrays. Overall design: Total RNAs were prepared from the white matter (optic nerve and optic tract) of wild-type or CD47 knockout mice. Total RNAs from five (wild-type) and four (CD47 knockout) different genotype-matched animals were pooled and subjected to the analysis on Affymetrix Gene Chip.

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2018-08-20
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