CNS Genome Atlas Project

CNS肿瘤和疾病基因组图谱项目(CNS-GAP)是一个标志性中枢神经系统疾病基因组学计划，分子表征了4028例原发性疾病和匹配的正常样本，涵盖10种CNS类型，包括胶质瘤、垂体肿瘤、脊索瘤等。该项目由北京神经外科研究所、国家神经系统疾病临床医学研究中心和中科院北京基因组研究所等机构共同参与，旨在建立CNS疾病基因组学的重要性，转变对CNS疾病的理解，并改变临床疾病治疗方式。The CNS Tumor and Disease Genome Atlas Project (CNS-GAP) is a landmark genomic program focused on central nervous system diseases. It has molecularly characterized 4028 primary disease specimens and their matched normal control samples, covering 10 categories of CNS tumors including glioma, pituitary tumor, chordoma and others. This project is jointly participated by institutions such as Beijing Neurosurgical Institute, National Clinical Research Center for Neurological Diseases, and Beijing Institute of Genomics, Chinese Academy of Sciences. Its core objectives are to establish the scientific significance of CNS disease genomics, advance the understanding of CNS disorders, and revolutionize clinical treatment practices for such diseases.

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背景概述

CNS Genome Atlas Project（CNS-GAP）是一个中枢神经系统疾病基因组学计划，对4028例原发性疾病和匹配正常样本进行分子表征，涵盖胶质瘤、垂体肿瘤等10种CNS类型。该项目由北京神经外科研究所等机构联合开展，旨在推动CNS疾病基因组学研究，转变疾病理解并优化临床治疗策略。