Comparison of SLEPR results using a series of cutoffs for selection of sample-level differentiated genes.

Comparison of permutated p-values and ranks of SLEPR analysis results of for human type 2 diabetes mellitus (DM2) data [23] with IGT and DM2 samples as Exclusion/Background class by using a series of different cutoffs (0.5, 0.75,1,1.25,1.5× of MADe) for selection of highly expressed genes as sample-level differentiated genes. The one-side MADe method selecting for highly expressed genes was used (see Materials And Methods section). The top 5 ranked terms from the case of 1XMADe are selected for comparison of permutated p-values and ranks for the same terms with those derived from other cutoffs. 1000 permutations were performed.