The cryptic diversity of hepadnavirus relatives
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Enveloped hepadnaviruses, non-enveloped nackednaviruses, and the recently discovered non-enveloped proto-nackednaviruses are closely related reverse-transcribing DNA viruses. Yet, the host range and diversity of proto-nackednaviruses remain unclear. Here, we report the discovery of 31 proto-nackednavirus like viruses (PnNVs) through deep genome-scale data mining. PnNVs are predominantly identified in distinct species of rotifers, implying the probable association between PnNVs and rotifers. Phylogenetic analyses show that PnNVs form at least five paraphyletic lineages, and nackednaviruses and hepadnaviruses nest within PnNVs, unveiling the cryptic diversity of reverse-transcribing DNA viruses.
创建时间：
2025-10-23
