Disruption of protein dynamics by an allosteric effector antibody
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Disruption of protein dynamics by an allosteric effector antibody Descriptor: Dihydrofolate reductase, Nanobody Authors: Oyen, D, Srinivasan, V, Steyaert, J, Barlow, J. Deposit date: 2009-10-12 Release date: 2010-10-20 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Constraining enzyme conformational change by an antibody leads to hyperbolic inhibition. J.Mol.Biol., 407, 2011
变构效应抗体介导的蛋白质动力学扰动 数据集描述:二氢叶酸还原酶(Dihydrofolate reductase)、纳米抗体(Nanobody) 作者:Oyen, D、Srinivasan, V、Steyaert, J、Barlow, J. 提交日期:2009-10-12 发布日期:2010-10-20 最后修改日期:2024-11-06 实验方法:X射线衍射(X-RAY DIFFRACTION),分辨率1.95埃(Å) 引用文献:通过抗体约束酶的构象变化可引发双曲线型抑制。《分子生物学杂志》(J.Mol.Biol.),第407卷,2011年
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2009-10-12



