Crystal structure of FDTS from T. maritima mutant (H53D) with FAD and dUMP
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Crystal structure of FDTS from T. maritima mutant (H53D) with FAD and dUMP Descriptor: 2'-DEOXYURIDINE-5'-MONOPHOSPHATE, CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, ... Authors: Mathews, I.I. Deposit date: 2013-04-22 Release date: 2014-03-26 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Flavin-Dependent Thymidylate Synthase as a Drug Target for Deadly Microbes: Mutational Study and a Strategy for Inhibitor Design. J Bioterror Biodef, Suppl 12, 2013
海栖热袍菌(T. maritima)突变体(H53D)的黄素依赖性胸苷酸合酶(Flavin-Dependent Thymidylate Synthase,FDTS)结合黄素腺嘌呤二核苷酸(FAD)与2'-脱氧尿苷-5'-单磷酸(dUMP)的晶体结构 配体描述:2'-脱氧尿苷-5'-单磷酸、氯离子、黄素腺嘌呤二核苷酸…… 作者:Mathews, I.I. 提交日期:2013-04-22 发布日期:2014-03-26 最后修改日期:2023-09-20 实验方法:X射线衍射(分辨率1.85埃) 引用文献:《黄素依赖性胸苷酸合酶作为致命微生物的药物靶点:突变研究与抑制剂设计策略》,刊载于《生物恐怖主义与生物防御杂志》(J Bioterror Biodef)增刊12,2013年



