Summary of association results with combined data from all stages of study.^a

aSNP: marker name (location information); A1: risk allele; A2: reference allele; FrCase: allele frequency of A1 in cases; FrCont: allele frequency of A1 in controls; P: p-values from allelic association analysis; OR: odds ratio with 95% confidence interval; Comb. P: combined p-value from meta-analysis. The strength of association of the three variants is shown. Chr6.24500625 in RBBP6 and Chr6.25681850 in USP31 remain highly significant after inclusion of more cases and controls.