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Structural basis for nucleolin recognition of MYC promoter G-quadruplex

NIAID Data Ecosystem2026-05-02 收录

G-四链体结构

核仁素结合位点

数据链接：

https://www.ncbi.nlm.nih.gov/sra/SRP530704 数据链接链接失效反馈

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资源简介：

CUT-Tag data of G-quadruplex forming sites and nucleolin binding sites in HeLa-S3 cells.

应用场景：

创建时间：

2025-05-06

G-四链体结构

端粒生物学

Structure of the Human G-quadruplex reveals a novel topology Descriptor: 5'-D(*(BRU)P*AP*GP*GP*GP*(BRU)P*TP*AP*GP*GP*GP*T)-3', POTASSIUM ION, SODIUM ION Authors: Parkinson, G.N, Lee, M.P.H, Neidle, S.

Protein Data Bank Japan2024-02-07 更新130

Additional file 4 of Telomeric retrotransposons show propensity to form G-quadruplexes in various eukaryotic species

端粒反转录转座子

G-四链体结构

Additional file 4.

DataCite Commons2023-04-13 更新60

LNA modified G-quadruplex with flipped G-tract and central tetrad

G-四链体结构

核酸化学修饰

LNA modified G-quadruplex with flipped G-tract and central tetrad

NIAID Data Ecosystem30

Structure and Stability of Human Telomeric G-Quadruplex with Preclinical 9-Amino Acridines

抗癌药物靶点研究

G-四链体结构

G-quadruplexes are higher-order DNA structures formed from guanine-rich sequences, and have been identified as attractive anticancer drug targets. Elucidating the three-dimensional structure of G-quad

NIAID Data Ecosystem60

Crystal structure of the major quadruplex formed in the promoter region of the human c-MYC oncogene

G-四链体结构

抗癌药物靶点研究

The c-MYC oncogene mediates multiple tumor cell survival pathways and is dysregulated or overexpressed in the majority of human cancers. The NHE III1 region of the c-MYC promoter forms a DNA quadruple

NIAID Data Ecosystem40

Structural basis for nucleolin recognition of MYC promoter G-quadruplex

资源简介：

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