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Global analysis of alternative splicing regulation by insulin and wingless signalling in Drosophila cells

ChEBI2010-05-06 更新2026-07-21 收录

植物可变剪接调控

果蝇细胞信号通路

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-14085 数据链接链接失效反馈

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Global analysis of alternative splicing regulation by insulin and wingless signalling in Drosophila cells

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创建时间：

2010-05-06

RNA结合蛋白

植物可变剪接调控

Purpose: Explore how DEK genome widely bind RNA and affect the alternative splicing in cancer Methods: DEK was overexpressed by transfecting HeLa cells with a DEK-overexpressing plasmid and RNA_seq wa

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Sam68 regulation of alternative splicing in the developing cerebellum

植物可变剪接调控

脑发育

We uncover a Sam68-dependent splicing program during cerebellar development. These events direct proper isoform expression of the genes required to guarantee the establishment of the correct spatial/t

Alliance of Genome Resources30

Cell type-specific alternative splicing during mammalian neuronal differentiation. Mus musculus

神经分化

植物可变剪接调控

Alternative precursor-mRNA splicing (AS) is a key regulation of gene expression and protein diversity. AS is highly happened in the nervous system and misregulation of AS caused neurological diseases.

NIAID Data Ecosystem30

RNA-Seq analysis in mutant zebrafish reveals role of U1C protein in alternative splicing regulation

植物可变剪接调控

斑马鱼基因功能

Precise 5' splice site recognition is essential for both constitutive and regulated pre-mRNA splicing. The U1 snRNP specific protein U1C is involved in this first step of spliceosome assembly and impo

NIAID Data Ecosystem50

Opposite expression of HNRNPA2B1 in cancer and senescent cells and its regulatory roles in senescence of cancer cells

癌细胞衰老

植物可变剪接调控

Splicing factor HNRNPA2B1 is associated with mouse lifespan and human longevity. It also plays a causal role in cancer development. However, whether it participates in cellular senescence, a biologica

NIAID Data Ecosystem30

Global analysis of alternative splicing regulation by insulin and wingless signalling in Drosophila cells

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