Additional file 2 of An interferon-related signature characterizes the whole blood transcriptome profile of insulin-resistant individuals—the CODAM study
Comparison of pancreatic islet transcriptome at 4hr intervals around the clock helps to identify genes that are cycling under the control of the circadian clock. We used Agilent microarrays to analyze
Intra-islet crosstalk between islet cells is critical in orchestrating the bodyâs response to changes in blood glucose levels, but is incompletely understood. In this study, we used transgenic mouse
β-cell Specific Kcnj11 -/- mice and their islets exhibited a hirtherto unkown switch in the major signaling pathway of G-protein coulpled receptors from Gs to Gq, and overall enhanced Gq signaling. Th