Progerin-induced transcriptional changes in Huntington's disease human pluripotent stem cells-derived neurons

Identification of transcriptional changes in Huntington's disease (HD) and normal (WT) human embryonic stem cells (hESC)- and induced pluripotent stem cells(iPSC)-derived striatal GABAergic neruons. RNA-seq (High-throughput Eukaryotic Digital Gene Expression (DGE)) of HD and WT human ESCs- and iPSCs-derived striatal GABAergic neurons, with and without progerin.