aHKera score-sorted MR genes were divided into 4 HK sets (HKI-HKIV) and 2 TS sets (TSI and TSII), each containing ∼2,000 genes (see Methods). bThe p values for the KEGG pathway were estimated using th
Differentially expressed gene sets were compared to Gene Ontology biological process annotations [50] and KEGG pathway annotations [51] using the hypergeometric distribution and corrected for multiple
