Data for: A Network Perspective on Comorbid Depression in Adolescents with Obsessive-compulsive Disorder

Participants The participants were 87 adolescents beginning treatment for OCD in the residential and intensive outpatient units of the Obsessive-Compulsive Disorder Center at Rogers Memorial Hospital. There were 41 (47.1%) males and 46 (52.9%) females, who ranged in age from 13 to 17 (M = 15.37, SD = 1.17). The racial/ethnic breakdown was Caucasian (n = 72), Asian (n = 10), Hispanic (n = 2), biracial (n = 2), and Black (n = 1). Board-certified staff psychiatrists, who are all experts in OCD and related disorders, used DSM-IV criteria to diagnose patients upon admission. These diagnoses were based on in-depth reviews of patients’ records from previous providers, information gathered by the hospital admissions staff, and an unstructured clinical interview with the adolescents and caretakers upon arrival at the treatment center. All participants received a primary diagnosis of OCD, and each consented for their data to be used in de-identified research. Current comorbid disorders according to these diagnoses were major depression (n = 21; 24.1%), depressive mood disorder not otherwise specified (n = 41; 47.1%, combined percentage = 71.3%), attention deficit hyperactivity disorder (n = 25; 28.7%), generalized anxiety disorder (n = 18; 20.7%), social anxiety disorder (n = 10; 11.5%), and tic/Tourette's syndrome (n = 8; 9.2%). Elevated comorbidities of current mood disorders is likely a result of the sample largely consisting of severe, clinically complex residential inpatients. Measures Children's Yale-Brown Obsessive Compulsive Scale Self-Report (CY-BOCS-SR; Scahill et al., 1997). The CY-BOCS-SR is a self-report questionnaire that evaluates the severity of OCD symptoms during the previous week. The scale includes 10 five-point Likert items which are summed to a score that ranges from 0-40 (a score of 16 or above signifies clinically significant severity). Reliability and validity of the self-report version of the scale are satisfactory (Scahill et al., 1997). The mean score in our sample was 26.1 (SD = 5.8, range = 24; Conelea, Schmidt, Leonard, Riemann, & Cahill, 2012). The 10 questions in the CY-BOCS-SR correspond to the 10 questions in the adult version of the scale (Y-BOCS; Goodman et al., 1989). Quick Inventory of Depressive Symptomatology (QIDS-SR; Rush et al., 2003). The QIDS-SR is a self-report questionnaire that evaluates the severity of depression symptoms. The scale includes 16 four-point Likert items summing to a total score ranging from 0-64. Reliability and validity of the scale are satisfactory (Rush et al., 2003). The mean score in our sample was 10.7 (SD = 5.9, range = 25).

### 参与者
本研究的参与者为87名初次接受强迫症（OCD，Obsessive-Compulsive Disorder）治疗的青少年，他们均在罗杰斯纪念医院强迫症诊疗中心的住院与强化门诊单元接受治疗。其中男性41名（占比47.1%），女性46名（占比52.9%），年龄介于13至17岁之间（平均年龄M=15.37，标准差SD=1.17）。种族/族裔分布如下：白人72例，亚裔10例，西班牙裔2例，混血2例，黑人1例。所有经专科委员会认证的精神科医师均为强迫症及相关障碍领域的专家，他们采用《精神障碍诊断与统计手册第四版》（DSM-IV）标准在患者入院时完成诊断。诊断依据涵盖三方面：对既往诊疗机构提供的患者病历进行深入审阅、医院入院工作人员收集的相关信息，以及患者与照料者抵达治疗中心后接受的非结构化临床访谈。所有参与者均被确诊为首要诊断为强迫症，且均签署知情同意书，同意将其去标识化后的数据用于科研。
根据上述诊断结果，受试者当前的共病障碍包括：重性抑郁症（n=21，占比24.1%）、未特定的抑郁心境障碍（n=41，占比47.1%，二者合并占比为71.3%）、注意缺陷多动障碍（n=25，占比28.7%）、广泛性焦虑障碍（n=18，占比20.7%）、社交焦虑障碍（n=10，占比11.5%）以及抽动/抽动秽语综合征（n=8，占比9.2%）。当前心境障碍共病率偏高，这可能与本样本以病情严重、临床特征复杂的住院患者为主有关。

### 测评工具
1. 儿童耶鲁-布朗强迫症量表自评版（CY-BOCS-SR，Children's Yale-Brown Obsessive Compulsive Scale Self-Report；Scahill等，1997）：该自评问卷用于评估受试者过去一周内的强迫症症状严重程度。量表包含10个5级李克特条目，总得分范围为0~40分（得分≥16分提示存在具有临床意义的症状严重程度）。该自评版本的信效度均表现良好（Scahill等，1997）。本样本的平均得分为26.1（SD=5.8，得分极差为24；Conelea, Schmidt, Leonard, Riemann, & Cahill, 2012）。CY-BOCS-SR的10个条目与成人版耶鲁-布朗强迫症量表（Y-BOCS，Yale-Brown Obsessive Compulsive Scale；Goodman等，1989）的10个条目一一对应。
2. 抑郁症状快速自评量表（QIDS-SR，Quick Inventory of Depressive Symptomatology；Rush等，2003）：该自评问卷用于评估抑郁症状严重程度，包含16个4级李克特条目，总得分范围为0~64分。该量表的信效度均表现良好（Rush等，2003）。本样本的平均得分为10.7（SD=5.9，得分极差为25）。