Datasets for "Large-Scale Imputation of KIR Copy Number and HLA Alleles in North American and European Psoriasis Case-Control Cohorts Reveals Association of Inhibitory KIR2DL2 with Psoriasis"

Here, we implemented KIR*IMP to impute KIR copy number and HLA*IMP to impute HLA alleles from single-nucleotide polymorphisms (SNPs) on chromosomes 6 and 19 in the discovery cohort from the PAGE consortium, University of California San Francisco, and the University of Dundee, and in a replication cohort from Kaiser Permanente Northern California. Stratified multivariate logistic regression that accounted for patient ancestry and high-risk HLA alleles revealed that KIR2DL2 copy number was significantly associated with psoriasis in the discovery cohort (p ≤ 0.05).