In the early stages of SARS-CoV-2 infection, non-structural protein 1 (Nsp1) inhibits the innate immune response by inserting its C-terminal helices into the mRNA entry channel of the ribosome and pro
aApparent dissociation constant estimated by ELISA. Mean and standard deviation from at least three separate experiments is shown, except where the mean from two experiments is shown with the range in
Tandem mass tag (TMT)-based quantitation is a strong modality for quantitative proteomics, as samples can be multiplexed, creating large-scale data sets with high precision and minimal missing values.