Argonaute proteins lie at the heart of the RNA-Induced Silencing Complex (RISC), wherein they use small RNA guides to recognize targets. Some Argonaute proteins can directly cleave their targets, wher
P granules are germ-cell-specific cytoplasmic structures containing RNA and protein and required for proper germ cell development in C. elegans. A new P-granule-associated protein, DEPS-1, whose loss
Aim of study The objective of these studies was to analyze the implication of slicer activity of AGO1 in the following molecular processes: • loading of siRNAs and miRNAs • stability of siRNAs and miR
