Mouse embryonic fibroblast (MEF) cells after 2, 3 or 4 days of inducible genetic deletion of Dicer1

ChEBI2013-05-10 更新2026-07-21 收录

基因功能敲除

RNA干扰机制

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-45886 数据链接链接失效反馈

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Mouse embryonic fibroblast (MEF) cells after 2, 3 or 4 days of inducible genetic deletion of Dicer1

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2013-05-10

The structure of human Argonaute-2 in complex with miR-20a

蛋白质-RNA复合物结构

RNA干扰机制

Argonaute proteins lie at the heart of the RNA-Induced Silencing Complex (RISC), wherein they use small RNA guides to recognize targets. Some Argonaute proteins can directly cleave their targets, wher

NIAID Data Ecosystem100

Next Generation Sequencing Facilitates Quantitative Analysis of Murine Salivary Gland Transcriptomes at 8 and 32 weeks. Next Generation Sequencing Facilitates Quantitative Analysis of Murine Salivary Gland Transcriptomes at 8 and 32 weeks

唾液转录组学

基因功能敲除

Purpose: Next-generation sequencing (NGS) has revolutionized systems-based analysis of cellular functions. The goal of this study is to compare NGS-derived salivary gland transcriptome profilings (RNA

NIAID Data Ecosystem60

Slicer activity of Arabidopsis AGO1 in siRNA biogenesis and miRNA target decay. Slicer activity of Arabidopsis AGO1 in siRNA biogenesis and miRNA target decay

RNA干扰机制

基因表达调控

Aim of study The objective of these studies was to analyze the implication of slicer activity of AGO1 in the following molecular processes: • loading of siRNAs and miRNAs • stability of siRNAs and miR

NIAID Data Ecosystem50

Small RNAs with 5′-Polyphosphate Termini Associate with a Piwi-Related Protein and Regulate Gene Expression in the Single-Celled Eukaryote Entamoeba histolytica

RNA干扰机制

基因沉默调控

Small interfering RNAs regulate gene expression in diverse biological processes, including heterochromatin formation and DNA elimination, developmental regulation, and cell differentiation. In the sin

NIAID Data Ecosystem70

DEPS-1 promotes P granule assembly and RNA interference in C. elegans germ cells

昆虫生殖细胞发育

RNA干扰机制

P granules are germ-cell-specific cytoplasmic structures containing RNA and protein and required for proper germ cell development in C. elegans. A new P-granule-associated protein, DEPS-1, whose loss

Alliance of Genome Resources50

Mouse embryonic fibroblast (MEF) cells after 2, 3 or 4 days of inducible genetic deletion of Dicer1

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