Inference of secreted-protein signaling activities in intercellular communication
收藏NIAID Data Ecosystem2026-05-02 收录
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资源简介：
The SecAct (Secreted Activity) model infers secreted-protein signaling activity from spatial, single-cell, and bulk transcriptomics data. Using SecAct, LY86 was identified and validated in vivo as a promising immunotherapy target. B16F10-Ly86 and B16F10-Vector tumors from mice that received 4 rounds of anti-PD-1 + anti-CTLA4 treatment were harvested and immediately snap-frozen in liquid nitrogen.
创建时间：
2025-07-08
