Foxp3 is a key downstream regulator of p53-mediated cellular senescence

ChEBI2015-08-13 更新2026-07-12 收录

细胞衰老机制

p53信号通路

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Foxp3 is a key downstream regulator of p53-mediated cellular senescence

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2015-08-13

The small molecule compound P2 in HCT116p53-/- and HCT116p53+/+ cells

癌症基因表达分析

p53信号通路

Global gene expression in HCT116p53-/- and HCT116p53+/+ cells HCT116p53-/- and p53+/+ were untreated and treated with P2 small molecule compound at 25 microM, total RNA was isolated and gene expressio

NIAID Data Ecosystem50

Enhanced expression of an insulin growth factor-like binding protein (mac25) in senescent human mammary epithelial cells and induced expression with retinoic acid.

细胞衰老机制

视黄酸调控基因表达

mac25, the subject of this report, was selected by the differential display of mRNA method in a search for genes overexpressed in senescent human mammary epithelial cells. mac25 had previously been cl

PubMed Central1995-05-09 更新30

Irreversibility of cellular aging and neoplastic transformation: a clonal analysis.

细胞衰老机制

肿瘤转化机制

Prolonged incubation of NIH 3T3 cells under the growth constraint of confluence results in a persistent impairment of proliferation when the cells are subcultured at low density and a greatly increase

PubMed Central1996-09-03 更新00

Age-associated dysregulation of peroxisomal matrix protein importing impairs intestinal stem cell differentiation and gut functions

细胞衰老机制

肠道干细胞

Age-associated dysregulation of peroxisomal matrix protein importing impairs intestinal stem cell differentiation and gut functions

integrated proteome resources50

The epigenetic aspects of cellular responses to irradiation

辐射表观遗传学

细胞衰老机制

The project is aimed at the analysis of epigenetic effects of cellular responses to irradiation. Here we aim to sequence genomes, epigenomes, and transcriptomes of cells exposed to different kinds of

NIAID Data Ecosystem30

Foxp3 is a key downstream regulator of p53-mediated cellular senescence

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