HPLC-HRMS-Based Integrated Lipidomics and Machine Learning Identifies Clinically Actionable Metabolic Signatures in ESCC

Untargeted lipidomics profiling was performed using liquid chromatography coupled with high-resolution Orbitrap mass spectrometry (LC-Orbitrap MS). Raw data were processed with Compound Discoverer 3.3本研究采用液相色谱联用高分辨轨道阱质谱（LC-Orbitrap MS）开展非靶向脂质组学表征分析，原始数据通过Compound Discoverer 3.3软件完成处理。