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资源简介：
Clinical characterisitics of MPN patients.
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创建时间：
2017-08-11
相关数据集
STAT1 is essential for hematopoietic stem cell function and maintains a MHC IIhi stem cell subset that resists myeloablation and neoplastic expansion. STAT1 is essential for hematopoietic stem cell function and maintains a MHC IIhi stem cell subset that resists myeloablation and neoplastic expansion
Adult hematopoietic stem cells (HSCs) are predominantly quiescent and can be activated in response to acute stress such as infection or cytotoxic insults. STAT1 is a pivotal mediator of interferon (IF
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Loss of cohesin in vivo alters adult stem cell homeostasis leading to myeloproliferative neoplasms
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JAK2V617F Impairs Lymphoid Differentiation in Myeloproliferative Neoplasms
Myeloproliferative neoplasms (MPNs) arise via the acquisition of a driver mutation in a single hematopoietic stem cell (HSC), often decades prior to the development of a clinical phenotype. The most c
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HiJAKing the hematopoietic system: a low-frequency JAK2V617F clone drives myeloproliferative neoplasm pathology
JAK2V617F is one of the most common mutations in clonal hematopoiesis of indeterminate potential (CHIP) and a major driver of myeloproliferative neoplasms (MPN). To determine the impact of the low fre
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Patient characteristics–Data set 2.
Age: Median and range; Disease duration: Median and range; V617F allele burden %: median and 95% confidence interval. HU = hydroxyurea, ANA = anagrelide.Patient characteristics–Data set 2.
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