Serum and glucocorticoid-induced kinase 1 (SGK1) regulates blood pressure and has been implicated in inflammation and fibrosis. We have tested whether increased SGK1 activity potentiates mineralocorti
Autism spectrum disorders (ASD) are ~4-times more common in males than females, and CHD8 (a chromatin remodeler)-related ASD shows a strong male bias (~5:1), although the underlying mechanism remains
Tabula Muris Senis是一个全面的小鼠衰老细胞图谱数据库，收录了从小鼠整个生命周期中不同器官的单细胞和批量RNA测序数据。该数据库提供了细胞类型特异性的分子和表型特征，用于研究哺乳动物在生命周期内经历的细胞生物学变化。项目包含20个器官的单细胞转录组分析，是理解基因在细胞类型特异性使用方式及其随时间变化的重要资源。
