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Gene expression profiles in skeletal muscle satellite cells lacking Dnmt1

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NIAID Data Ecosystem2026-03-12 收录
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To identify the target genes of Dnmt1 in skeletal muscle satellite cells, we generated satellite cell specific Dnmt1 KO using Pax7-CreERT2 and Dnmt1 flox mice. After Tamoxifen (cKO) or vehicle (Control) treatment for 5 consecutive days, mice were euthanized and muscle satellite cells were collected by FACS sorting and total RNA were extracted. Overall design: mRNA profiles of muscle satellite cells obtained from control and satellite cell specific Dnmt1 KO mice were generated by sequencing, in triplicates, using Illumina Miseq.

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2021-04-10
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