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Quantitative Genomic Analysis of RecA Protein Binding During DNA Double-Strand Break Repair Reveals RecBCD Action in vivo

ChEBI2015-08-11 更新2026-07-12 收录

DNA双链断裂修复

蛋白质结合定量分析

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-71249 数据链接链接失效反馈

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Quantitative Genomic Analysis of RecA Protein Binding During DNA Double-Strand Break Repair Reveals RecBCD Action in vivo

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创建时间：

2015-08-11

DNA双链断裂修复

NHEJ非同源末端连接

RIF1 acts downstream of 53BP1 to coordinate DNA double strand break repair pathway choice between non-homologous end joining (NHEJ) and homologous recombination (HR). Here we identified ASF1 as an end

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Cancer Cell Resistance to IFN? Can Occur via Enhanced Double-Strand Break Repair Pathway Activity [CRISPR screen]

癌症免疫治疗耐药性

DNA双链断裂修复

The pleiotropic cytokine interferon-gamma (IFN?) is known to be associated with cytostatic, anti-proliferation, and pro-apoptosis functions in cancer cells. However, cancer cells can become resistant

NIAID Data Ecosystem70

BCL10 is recruited to sites of DNA damage to facilitate DNA double-strand break repair

DNA双链断裂修复

DNA损伤机制

Recent studies have found BCL10 can localize to the nucleus and that this is linked to tumor aggression and poorer prognosis. These studies suggest that BCL10 localization plays a novel role in the nu

Taylor & Francis Group2019-10-25 更新50

Transcriptionally active chromatin channels DNA double-strand breaks to RAD51-dependent repair. Transcriptionally active chromatin channels DNA double-strand breaks to RAD51-dependent repair

DNA双链断裂修复

染色质依赖性修复选择

Cells have developed effective mechanisms, namely homologous recombination (HR) and non-homologous end-joining (NHEJ), to repair DNA double-strand breaks (DSBs), which are considered to be the most de

NIAID Data Ecosystem100

A Role for the Malignant Brain Tumour (MBT) Domain Protein LIN-61 in DNA Double-Strand Break Repair by Homologous Recombination

DNA双链断裂修复

同源重组机制

Malignant brain tumour (MBT) domain proteins are transcriptional repressors that function within Polycomb complexes. Some MBT genes are tumour suppressors, but how they prevent tumourigenesis is unkno

NIAID Data Ecosystem50

Quantitative Genomic Analysis of RecA Protein Binding During DNA Double-Strand Break Repair Reveals RecBCD Action in vivo

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