Small RNA-seq profiling of a directed differentiation model that programs human embryonic stem cells toward the small intestinal lineage

Small RNA-seq profiling of a directed differentiation organoid model revealed changing microRNA landscapes of early human small intestinal development Small RNA-seq was performed for the following stages of directed differentiation: human embryonic stem cell (hESC), definitive endoderm (DE), duodenal (Duo) spheroid, ileal (Ile) spheroid, Duo organoid and Ile organoid.