Stereoselective Synthesis of Azetidines and Pyrrolidines from <i>N</i>-<i>tert</i>-Butylsulfonyl(2-aminoalkyl)oxiranes
收藏NIAID Data Ecosystem2026-03-06 收录
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Base-induced cyclization of enantiopure (2-aminoalkyl)oxiranes allowed the stereospecific formation of pyrrolidin-3-ols and/or 2-(hydroxymethyl)azetidines, depending on the reaction conditions. The oxidation of 2-(hydroxymethyl)azetidines led to azetidine-2-carboxylic acids in high yields.
创建时间:
2016-02-25



