Exploring Antibiotic Resistance in Diverse Homologs of the Dihydrofolate Reductase Protein Family through Broad Mutational Scanning

This compressed zip file contains the of DHFR (variant-barcode) mapping and NGS barcode count files used in the RMD analysis scripts for the publication: Exploring antibiotic resistance in diverse homologs of the dihydrofolate reductase protein family through broad mutational scanningKarl J. Romanowicz et al. , Sci. Adv.11,eadw9178(2025). DOI:10.1126/sciadv.adw9178The RMD analysis scripts are available here:https://github.com/PlesaLab/DHFRThe folder structure within the zip file matches the RMD loading calls.Additional links:RPubs: Rendered CodeNCBI BioProject: PRJNA1189478 for raw .fastq filesFigShare Repository: Processed DHFR fitness scores.