Crystal structure of Keap1 in complex with monoethyl fumarate (MEF)

Crystal structure of Keap1 in complex with monoethyl fumarate (MEF) Descriptor: (~{Z})-4-ethoxy-4-oxidanylidene-but-2-enoic acid, ACETATE ION, Kelch-like ECH-associated protein 1, ... Authors: Padmanabhan, B, Unni, S, Deshmukh, P, Krishnappa, G. Deposit date: 2020-05-21 Release date: 2020-08-05 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Structural insights into the multiple binding modes of Dimethyl Fumarate (DMF) and its analogs to the Kelch domain of Keap1. Febs J., 288, 2021Keap1与富马酸单乙酯（monoethyl fumarate, MEF）复合物的晶体结构 配体描述：(~Z)-4-乙氧基-4-氧代-2-丁烯酸、乙酸根离子、Kelch样ECH相关蛋白1（Kelch-like ECH-associated protein 1, Keap1）…… 作者：Padmanabhan, B、Unni, S、Deshmukh, P、Krishnappa, G 沉积日期：2020-05-21 发布日期：2020-08-05 最后修改日期：2023-11-29 实验方法：X射线衍射（X-RAY DIFFRACTION，分辨率1.95 Å） 引用文献：《关于富马酸二甲酯（Dimethyl Fumarate, DMF）及其类似物与Keap1 Kelch结构域多结合模式的结构洞察》，FEBS J., 288, 2021