Cryo-EM structure of an active Kaposi's Sarcoma-Associated Herpesvirus-G Protein-Coupled Receptor (KSHV-GPCR) in complex with Gi protein

Cryo-EM structure of an active Kaposi's Sarcoma-Associated Herpesvirus-G Protein-Coupled Receptor (KSHV-GPCR) in complex with Gi protein Descriptor: G protein-coupled receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... Authors: Liu, Y.Z, Liu, A.J. Deposit date: 2023-07-20 Release date: 2024-07-24 Last modified: 2025-07-02 Method: ELECTRON MICROSCOPY (2.81 Å) Cite: Structural insights into KSHV-GPCR constitutive activation and CXCL1 chemokine recognition. Proc.Natl.Acad.Sci.USA, 121, 2024激活态卡波西肉瘤相关疱疹病毒G蛋白偶联受体（KSHV-GPCR）与Gi蛋白复合物的冷冻电镜（Cryo-EM）结构 描述项：G蛋白偶联受体、鸟嘌呤核苷酸结合蛋白G(I)/G(S)/G(T)亚基β-1、鸟嘌呤核苷酸结合蛋白G(i)亚基α-1…… 作者：Liu, Y.Z、Liu, A.J. 存档日期：2023-07-20 发布日期：2024-07-24 最后修改日期：2025-07-02 实验方法：电子显微镜（分辨率2.81埃） 引用文献：《卡波西肉瘤相关疱疹病毒G蛋白偶联受体组成型激活及CXCL1趋化因子识别的结构解析》，发表于《美国国家科学院院刊》（Proc. Natl. Acad. Sci. USA），2024年，第121卷