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AD 133 Transcriptome data
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2025-04-13
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Additional file 12: Table S7. of An integrative genome-wide transcriptome reveals that candesartan is neuroprotective and a candidate therapeutic for Alzheimerâs disease
IPA of diseases and functions annotation of genes preferentially expressed in cerebrovascular endothelial cells. Table S7 notes the diseases and functions that are upregulated in Alzheimerâs disease
NIAID Data Ecosystem70
MOESM3 of Genetic perturbations of disease risk genes in mice capture transcriptomic signatures of late-onset Alzheimer’s disease
Additional file 3: Table S3. Mouse modules of co-expressed genes. Summaries of the 26 mouse modules of co-expressed genes. In sheet 1, genes in each mouse modules were listed. Sheet 2 depicts mouse mo
NIAID Data Ecosystem50
APP/PS1 mice characterization and time progression
RNA samples from the cerebral cortex of APP/PS1 and WT mouse littermates aged 3, 6 and 12 months were analyzed using the Affymetrix Genechip Mouse Gene 1.1 ST Array. The APP-PS1 transgenic mouse expre
Alliance of Genome Resources20
Transcriptional Alterations Related to Neuropathology and Clinical Manifestation of Alzheimer’s Disease
Alzheimer’s disease (AD) is the most common cause of dementia in the human population, characterized by a spectrum of neuropathological abnormalities that results in memory impairment and loss of othe
NIAID Data Ecosystem60
Whole hippocampus RNA seq on (SCDi Cayman 10566) and Vehicle (DMSO) in 10 month old WT and 3xTg-AD mice
RNA was extracted from microdissected hippocampi from 10-month old DMSO or SCDi (Cayman 10566) ICV treated WT or 3xTg-AD mice. Overall design: 28 day ICV infusion of DMSO or SCDi (Cayman 10566)
NIAID Data Ecosystem40
