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Classification accuracy using commonly amplified 16S hypervariable regions, V1-V2 and V3-V4, the entire 16S and rRNA operons, and shotgun sequencing of the entire genome.

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NIAID Data Ecosystem2026-03-13 收录
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While short hypervariable regions perform poorly and inconsistently across these samples, classification based on the entire rRNA operon (~4,500bp) approaches classification accuracy of whole-genome sequencing.

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2021-10-28
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