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mRNA expression profiles in primary microglia cells treated with R848, IFN-a, and R848+ IFN-a

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Using RNA-seq, we have reported signaling crosstalk between IFN-a and R848 at the level of transcriptomes highlighting synergsitic gene expression dynamics upon different receptors signaling in microglia cells Overall design: Comparative study of the effects of control versus R848, IFN-a and R848+IFN-a treated PM cells, were generated by deep sequencing on an Illumina HiSeq 2500 (101 cycles PE lane).

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2018-09-20
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