Sequences of isolated anti-EGFR aptamers.

NIAID Data Ecosystem2026-03-07 收录

适配体序列分析

EGFR靶向药物

数据链接：

https://figshare.com/articles/dataset/_Sequences_of_isolated_anti_EGFR_aptamers_/438253 数据链接链接失效反馈

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资源简介：

Only the random sequence portions of the aptamers are shown. Substitutions relative to Aptamer E01 are shown in bold italics.

创建时间：

2011-06-08

Highly optimized CNS penetrant inhibitors of EGFR Exon20 Insertion Mutations

EGFR靶向药物

中枢神经系统渗透抑制剂

Highly optimized CNS penetrant inhibitors of EGFR Exon20 Insertion Mutations Descriptor: 1-[2-[5-(1,3-benzoxazol-4-yl)-2,4-bis(fluoranyl)phenyl]-3-pyrimidin-4-yl-4,6-dihydropyrrolo[3,4-d]imidazol-5-yl

Protein Data Bank Japan2025-02-26 更新80

Sequences of aptamers investigated in affinity and inhibition assays; the sequences of APT-15 and APT-29 in bivalent aptamers are underlined.

适配体序列分析

分子识别

Sequences of aptamers investigated in affinity and inhibition assays; the sequences of APT-15 and APT-29 in bivalent aptamers are underlined.

NIAID Data Ecosystem40

Crystal Structure of EGFR T790M mutant in complex with naquotinib

EGFR靶向药物

非小细胞肺癌治疗

Crystal Structure of EGFR T790M mutant in complex with naquotinib Descriptor: 6-ethyl-3-[[4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]amino]-5-[(3R)-1-prop-2-enoylpyrrolidin-3-yl]oxy-pyrazin e-

Protein Data Bank Japan2024-10-30 更新30

ADMET parameters for T-1-MTA and erlotinib.

EGFR靶向药物

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A new semisynthetic derivative of the natural alkaloid, theobromine, has been designed as a lead antiangiogenic compound targeting the EGFR protein. The designed compound is an (m-tolyl)acetamide theo

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EGFR L858R/V948R in complex with osimertinib and allosteric inhibitor JBJ-09-063

EGFR靶向药物

变构抑制剂

EGFR L858R/V948R in complex with osimertinib and allosteric inhibitor JBJ-09-063 Descriptor: (2R)-2-(5-fluoro-2-hydroxyphenyl)-2-{6-[4-(1-methylpiperidin-4-yl)phenyl]-1-oxo-1,3-dihydro-2H-isoindol-2-y

Protein Data Bank Japan2024-11-20 更新40

Sequences of isolated anti-EGFR aptamers.

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