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Tumor cell-specific inhibition of MYC function using small molecule inhibitors of the HUWE1 ubiquitin ligase

ChEBI2014-10-22 更新2026-07-21 收录

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泛素化调控

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-MTAB-1890 数据链接链接失效反馈

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资源简介：

Tumor cell-specific inhibition of MYC function using small molecule inhibitors of the HUWE1 ubiquitin ligase

应用场景：

创建时间：

2014-10-22

癌症靶向治疗

RAS信号通路抑制

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All data from source data

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Relationships between Signaling Pathway Usage and Sensitivity to a Pathway Inhibitor: Examination of Trametinib Responses in Cultured Breast Cancer Lines

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Cellular signaling pathways involving mTOR, PI3K and ERK have dominated recent studies of breast cancer biology, and inhibitors of these pathways have formed a focus of numerous clinical trials. We ha

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癌细胞重编程

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Table S10 from EML4−ALK Variant-Specific Genetic Interactions Shape Lung Tumorigenesis

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Supplementary Table 10 shows the proportional tumor size remaining after lorlatinib treatment, including the confidence intervals and significance.

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