Silver-Catalyzed Radical Cascade Sulfonation/Cycloaddition for the Construction of Multifunctional Succimides Containing Separable Z/E‑Isomers
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A silver-catalyzed cascade cycloaddition of aza-1,6-enynes, affording multifunctional succimide frameworks initiated by the arylsulfonyl radical addition, has been developed. This process shows mild reaction conditions, excellent structural selectivity, and broad functional group tolerance. In addition, the Z/E-isomers can be easily separated, which provides an efficient method for obtaining pure Z/E-configuration products.
创建时间：
2021-01-21
