Antimicrobial peptide resistance in human gut microbial communities. Antimicrobial peptide resistance in human gut microbial communities

The goal of this study was to identify human gut microbes that are sensitive to the cationic antimicrobial peptide polymyxin B (PMB). Fecal samples from healthy human donors were plated under anaerobic conditions on varying concentrations of PMB and colonies subjected to 16S rRNA sequencing targeting variable region 4.