Single-cell CRISPR screens allow for the exploration of mammalian gene function and genetic regulatory networks, but their utility has been limited in part by their reliance on indirect sgRNA indexing
Invasive candidiasis caused by non-albicans species has been on the rise in recent years, with Candida glabrata being the second most common etiological agent. Currently, we have limited knowledge abo
In the United States, racial biases have been tied to poor health outcomes and difficulties accessing healthcare. There is growing evidence that structural racism is linked to the uneven experience of
PCR products were generated using genome-wide CRISPR libraries as template DNA. Subsequently, PCR products are pooled and subjected to Illumina library preparation. The library will be sequenced using
In vitro and in vivo growth screen data, HCC827 cells, Source data for Fig 1. Mini-library CRISPRi screen in HCC827 cells, raw data. The read counts for each sgRNA in all in vitro and in vivo (flank a
