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Genome-wide nucleotide-resolution mapping of DNA replication patterns, single-strand breaks and lesions by GLOE-Seq

Alliance of Genome Resources2026-08-01 收录

DNA复制模式

基因组损伤

数据链接：

https://www.yeastgenome.org/dataset/GSE134225 数据链接链接失效反馈

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资源简介：

This SuperSeries is composed of the SubSeries listed below.

本超系列（SuperSeries）由以下列出的子系列（SubSeries）组成。

应用场景：

DNA复制叉稳定性

基因组损伤

Transient obstruction of DNA polymerase progression activates the ATR checkpoint kinase, which suppresses fork breakage, strand resection, and RPA accumulation. Herein, we use a developed DNA break-de

NIAID Data Ecosystem90

Genome-wide maps of apurinic sites (AP-sites) and 8-oxoG derived secondary AP-sites

DNA氧化损伤

基因组损伤

We developed a novel method, AP-seq, capable of mapping apurinic sites and 8-oxo-7,8-dihydroguanine bases at approximately 250bp resolution on a genome-wide scale. We directly demonstrate that the acc

NIAID Data Ecosystem80

Oryza sativa Raw sequence reads. Oryza sativa

植物基因工程

基因组损伤

As a means to understand the mechanistic underpinnings of biolistic transformation, we transformed linear and circular DNA molecules into rice and maize, and subjected the lines to whole genome sequen

NIAID Data Ecosystem50

CPD-seq map of UV damage formation in isolated human genomic DNA

DNA辐射损伤

基因组损伤

UV-induced CPDs were mapped in isolated human genomic DNA following 80J/m2 of UVC irradiation Overall design: UV-induced cyclobutane pyrimidine dimers (CPDs) were mapped across the genome of isolated

NIAID Data Ecosystem90

Sequencing the mouse genome for the oxidatively modified base 8-oxo-7,8-dihydroguanine by OG-Seq

基因组损伤

DNA修复

Oxidative damage to the genome can yield the base 8-oxo-7,8-dihydroguanine (OG). A method was developed to sequence OG on the genome scale at a resolution of 150 base pairs that we call OG-Seq. This a

NIAID Data Ecosystem70

Genome-wide nucleotide-resolution mapping of DNA replication patterns, single-strand breaks and lesions by GLOE-Seq

资源简介：

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