Genome-wide nucleotide-resolution mapping of DNA replication patterns, single-strand breaks and lesions by GLOE-Seq

Alliance of Genome Resources2026-08-01 收录

DNA复制模式

基因组损伤

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https://www.yeastgenome.org/dataset/GSE134225 数据链接链接失效反馈

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This SuperSeries is composed of the SubSeries listed below.

cisplatin-damaged gene locus-replicate 2-L-R1

基因组损伤

顺铂治疗

Cisplatin is a DNA-targeting chemotherapeutic, yet its damaged gene loci are largely unexplored. We utilized a forward chemical genetics strategy to map 7578 cisplatin-damaged genes (CDGs) with >12 fo

NIAID Data Ecosystem70

Sequencing the mouse genome for the oxidatively modified base 8-oxo-7,8-dihydroguanine by OG-Seq

基因组损伤

DNA修复

Oxidative damage to the genome can yield the base 8-oxo-7,8-dihydroguanine (OG). A method was developed to sequence OG on the genome scale at a resolution of 150 base pairs that we call OG-Seq. This a

NIAID Data Ecosystem40

Genomewide nucleotide-resolution mapping of single-strand breaks and lesions by GLOE-Seq [UV treatment]. Genomewide nucleotide-resolution mapping of single-strand breaks and lesions by GLOE-Seq [UV treatment]

基因组损伤

UV诱导DNA损伤

Numerous methods are available for the mapping of DNA lesions ranging from double-strand breaks (DSBs) to incorporated ribonucleotides. We now present a technology based on the Genomewide Ligation of

NIAID Data Ecosystem30

Nucleotide resolution genome-wide mapping of 8-oxoG damage

DNA氧化损伤定位

基因组损伤

Single nucleotide resolution sequencing of DNA damage is required to decipher the complex causal link between the identity and location of DNA adduct and mutation patterns in the genome. We coupled th

NIAID Data Ecosystem50

Neuronal Enhancers are Hotspots for DNA Single-Strand Break Repair [RNA-seq]

神经元DNA单链断裂修复

基因组损伤

Defects in DNA repair frequently lead to neurodevelopmental and neurodegenerative diseases, underscoring the particular importance of DNA repair in long-lived post-mitotic neurons. The cellular genome

NIAID Data Ecosystem30

Genome-wide nucleotide-resolution mapping of DNA replication patterns, single-strand breaks and lesions by GLOE-Seq

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