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Genome wide occupancy of SUMO machinery in proliferative and Ras-induced senescent human primary fibroblasts

ChEBI2013-07-24 更新2026-07-21 收录

SUMO化修饰

细胞衰老机制

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-42211 数据链接链接失效反馈

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资源简介：

Genome wide occupancy of SUMO machinery in proliferative and Ras-induced senescent human primary fibroblasts

应用场景：

创建时间：

2013-07-24

染色质蛋白

SUMO化修饰

SU-DHL-5 cells display limited expression of the SUMO isopeptidase SENP6. In this experiment, the chromatin associated fraction of SU-DHL-5 cells was analysed by mass spectrometry. SU-DHL-5 cells were

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Gene expression profiling of replicative and induced senescence

细胞衰老机制

RNA-seq表达分析

Cellular senescence is a cell cycle arrest accompanied by high expression of cyclin dependent kinase inhibitors which counteract overactive growth signals, which serves as a tumor suppressive mechanis

Taylor & Francis Group2020-05-18 更新50

Genome-wide levels of RNA polymerase II (RNAPII) in normally growing or heat-shocked wild-type and sumolyation-deficient ubc9-6 yeast strains

转录调控机制

SUMO化修饰

Many transcription-related proteins are known to be modified by SUMO post-translational modification in yeast, plants, humans and other eukaryotes. We are interested in understanding how cells use sum

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Inhibiting NLRP3 Signaling in Aging Podocytes Improves Their Life- and Health-span

细胞衰老机制

NLRP3炎症小体

The decrease in the podocyte's lifespan and health-span that typify healthy kidney aging cause a decrease in their normal structure, physiology and function. The ability to halt and even reverse these

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Age-associated dysregulation of peroxisomal matrix protein importing impairs intestinal stem cell differentiation and gut functions

细胞衰老机制

肠道干细胞

Age-associated dysregulation of peroxisomal matrix protein importing impairs intestinal stem cell differentiation and gut functions

integrated proteome resources50