DNA methylation in melanoma is connected to gene expression phenotypes and MITF pathway expression.

ChEBI2015-05-17 更新2026-07-21 收录

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MITF信号通路分析

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-51547 数据链接链接失效反馈

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DNA methylation in melanoma is connected to gene expression phenotypes and MITF pathway expression.

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2015-05-17

DNA methylation profile from three pairs of melanoma cell lines (WM115/W226-4 ; M4Be/M4BeS2 ; M4Be/TW12)

黑色素瘤表观遗传

肿瘤侵袭性

DNA methylation profile from three pairs of cell lines (WM115/W226-4 ; M4Be/M4BeS2 ; M4Be/TW12) with common genetic background (human) and derived in tree different organisms (human-rat-mouse) were an

NIAID Data Ecosystem90

RNA-seq of UV irradiated human epidermal melanocytes from neonatal foreskin, HEMn-DP2.. RNA-seq of UV irradiated human epidermal melanocytes from neonatal foreskin, HEMn-DP2.

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UV辐射与DNA甲基化

UVR is the principal risk factor for melanoma development. While the role of UVR in DNA mutagenesis is incontrovertible, it remains controversial what role UVR-induced mutations play in melanoma genes

NIAID Data Ecosystem50

Conservation of global DNA methylation patterns due to cell culture establishment from human melanoma tissue. Conservation of global DNA methylation patterns due to cell culture establishment from human melanoma tissue

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细胞系甲基化保留

Cell lines are a critical in vitro model and heavily used to unravel mechanisms of cancer cell biology. However, limited data is available to assess whether DNA methylation patterns in tissues are ret

NIAID Data Ecosystem20

The DNA methylation landscape of human melanoma [RNA-Seq]

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甲基化DNA生物标志物

Melanoma genomes are often characterized by large numbers of sunlight-induced mutations. However, epigenetic alterations, in the form of aberrant DNA methylation patterns, are also abundant. Using MIR

NIAID Data Ecosystem50

Developmental chromatin programs determine oncogenic competence in melanoma [Cut&Run]

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发育染色质调控

We perfomed Cut&Run for ATAD2, MYC and SOX10 in 3xKO ATAD2 dox melanocytes and 3xKO dox melanocytes. We used 10'000 cells per condition and the protocol was performed as in Skene et al., 2018. We coul

NIAID Data Ecosystem20

DNA methylation in melanoma is connected to gene expression phenotypes and MITF pathway expression.

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