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DNA damage responses activate a multi-functional genetic program in murine bone marrow-derived macrophages

ChEBI2015-07-03 更新2026-07-12 收录

DNA损伤响应

巨噬细胞遗传调控

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-70467 数据链接链接失效反馈

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资源简介：

DNA damage responses activate a multi-functional genetic program in murine bone marrow-derived macrophages

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创建时间：

2015-07-03

DNA损伤响应

p53-ChIP-Seq分析

CSL is a key transcription factor, mostly acting as a repressor. While known as main effector of Notch signaling, it can also play Notch-independent functions. Despite the wide interest in CSL, the me

NIAID Data Ecosystem50

DNA-PKcs RNASeq data: DNA-PKcs wilde-type or kinase-dead protein regulate basal and etoposide-induced gene expression changes

DNA损伤响应

转录组学分析

Maintenance of the genome is essential for cell survival, and impairment of the DNA damage response is associated with multiple pathologies including cancer and neurological abnormalities. DNA-PKcs is

NIAID Data Ecosystem10

Chk2 is dispensable for p53-mediated G(1) arrest but is required for a latent p53-mediated apoptotic response

DNA损伤响应

细胞周期检查点

In response to genotoxic stress, mammalian cells can activate cell cycle checkpoint pathways to arrest the cell for repair of DNA damage or induce apoptosis to eliminate damaged cells. The checkpoint

PubMed Central2002-07-03 更新10

Translational and transcriptional responses of fission yeast to MMS

DNA损伤响应

裂殖酵母基因表达

Translational and transcriptional responses of fission yeast to MMS

ChEBI2020-11-18 更新40

Genome-wide redistribution of H3K27me3 is linked to genotoxic stress and defective growth. Neurospora crassa

表观遗传调控

DNA损伤响应

H3K9 methylation directs heterochromatin formation by recruiting multiple HP1-containing complexes that deacetylate histones and methylate cytosine bases in DNA. In Neurospora crassa, a single H3K9 me

NIAID Data Ecosystem10

DNA damage responses activate a multi-functional genetic program in murine bone marrow-derived macrophages

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