Mabs escape mutants against MmpL3 targeting drug

NIAID Data Ecosystem2026-05-10 收录

分枝杆菌耐药性

MmpL3靶点突变

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https://www.ncbi.nlm.nih.gov/sra/SRP646339 数据链接链接失效反馈

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资源简介：

Objective of this WGS was to identify the SNP's among escape mutants (resistant mutants) generated in presence of bactericidal concentration of novel compound targeting MmpL3.

创建时间：

2026-03-01

iValiD-TB: A fully characterized Mycobacterium tuberculosis dataset for antimicrobial resistance bioinformatics workflow validations

分枝杆菌耐药性

临床NGS检测验证

For clinical assay validations, well-characterized samples are essential for assessing methodology sensitivity and specificity. To support the community in the development of clinical next-generation

DataONE2024-05-08 更新60

Data Sheet 1_Risk factors and drug resistance of non-tuberculous mycobacteria in HIV/AIDS patients: a retrospective study in southern China.csv

HIV共感染流行病学

分枝杆菌耐药性

BackgroundThe incidence and infection rate of Non-tuberculous Mycobacteria (NTM) are increasing across different regions, with regional variations in the types, distribution, and drug resistance profi

NIAID Data Ecosystem40

Correlation between Quinolone Susceptibility Patterns and Sequences in the A and B Subunits of DNA Gyrase in Mycobacteria

分枝杆菌耐药性

喹诺酮类药物机制

The in vitro activities of seven quinolones and the sequences of the quinolone resistance-determining regions (QRDR) in the A and B subunits of DNA gyrase were determined for 14 mycobacterial species.

PubMed Central20

Supplementary Table S5

微生物基因组学

分枝杆菌耐药性

Metadata, genome statistics and species classification of all Portuguese Mycobacterium avium complex isolates enrolled in the present study. NUT - Nomenclature of Territorial Units for Statistics; mDS

DataCite Commons2025-02-25 更新50

Genetic diversity and drug susceptibility profiles of Mycobacterium tuberculosis obtained from Saint Peter’s TB specialized Hospital, Ethiopia

分枝杆菌耐药性

结核病流行病学

Background Tuberculosis (TB) is one of the major public health problems in Ethiopia. Data on genetic diversity and resistance profile of circulating TB strains is critical for informing the national T

NIAID Data Ecosystem30

Mabs escape mutants against MmpL3 targeting drug

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