Dual targeting of processive transcription for Myc-driven circuitry in medulloblastoma

NIAID Data Ecosystem2026-05-02 收录

母细胞瘤转录组学

Myc驱动转录

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE267473 数据链接链接失效反馈

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资源简介：

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

创建时间：

2025-01-13

To identify transcripts that are differentially expressed in the MYCN amplified vs MYCN non-amplified cell lines using Next Generation Sequencing

母细胞瘤转录组学

MYCN扩增差异表达基因

The aims of this study are to compare transcripts that are differentially expressed in the MYCN amplified compare to the MYCN non-amplified neuroblastoma cell lines, in particular, long non-coding RNA

NIAID Data Ecosystem70

Neuradapt: Structural Optimization and Transcriptomic Analysis. Neuradapt: Structural Optimization and Transcriptomic Analysis

HIF抑制剂

母细胞瘤转录组学

A newly developed “branched tail” oxyquinoline, neuradapt, and its variants are an order of magnitude more effective HIF prolyl hydroxylase (HIF PHD) inhibitors than roxadustat and vadadustat in HIF1

NIAID Data Ecosystem30

Discover – MB Gene Expression

母细胞瘤转录组学

辐射剂量响应差异表达

Bulk RNA sequencing was performed on medulloblastoma samples collected from Ptch1⁺/⁻ mice following neonatal γ irradiation (0 Gy, 0.1 Gy, 2 Gy). Libraries were generated from total RNA extracted from

DataCite Commons2026-03-25 更新20

RNAseq in IMR-32 neuroblastoma cells

母细胞瘤转录组学

RNA结合蛋白与应激响应

IMR-32 cells were subjected to lentiviral YRNA infection or nELAVL RNAi and/or UV stress followed by RNAseq analysis to monitor RNA level changes Overall design: RNA from IMR-32 cells was Trizol extra

NIAID Data Ecosystem50

Transcriptomic analysis of cell-of-origin CNS neuroblastoma, FOXR2 activated [CUT&RUN]

母细胞瘤转录组学

FOXR2转录因子功能

The transcription factor FOXR2 is the universal driver of childhood central nervous system neuroblastoma, FOXR2 activated (NB-FOXR2). NB-FOXR2 tumors arise exclusively in the brain hemispheres, and de

NIAID Data Ecosystem20

Dual targeting of processive transcription for Myc-driven circuitry in medulloblastoma

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