Results from J774A.1 CRISPR screens: Hc/uninfected.

Comma-separated-values (CSV) file showing the casTLE analysis [51] results comparing the guide abundances in the Hc infected and uninfected J774A.1 pools. Each row corresponds to a gene whose targeting sgRNA sequences were identified in at least one screen replicate (count threshold = 25). The columns are shown as follows: GeneID: ENSEMBL gene ID; Symbol: EMSEMBL gene symbol; GeneInfo, Localization, Process, and Function GO-terms assigned to the gene; #Elements: the number of guides identified in either replicate (1 or 2); casTLE Effect: the magnitude and sign of the effect for one screen replicate (1 or 2) or a combination of the replicates (Combo), where a negative effect indicates guide depletion in the Hc-infected pool and a positive effect indicates guide enrichment in the Hc-infected pool compared to the uninfected pool; casTLE Score: the casTLE confidence score; Signed Combo casTLE score: the Combo casTLE confidence score with the sign of the effect; P value: indicates the p-value of the gene effect; 5% FDR: 1 indicates a gene is a screen hit under a 5% FDR cutoff, and 0 indicates a gene is not a screen hit under a 5% FDR cutoff; 10% FDR: 1 indicates a gene is a screen hit under a 10% FDR cutoff, and 0 indicates a gene is not a screen hit under a 10% FDR cutoff; Minimum Effect Estimate: Minimum effect estimate using a 95% credible interval; Maximum Effect Estimate: Maximum effect estimate using a 95% credible interval. (CSV)