CD8+ T cell responsiveness to anti-PD-1 is epigenetically regulated by Suv39h1 in melanomas

NIAID Data Ecosystem2026-03-13 收录

抗PD-1免疫治疗耐药

黑色素瘤表观遗传

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE198423 数据链接链接失效反馈

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This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

创建时间：

2022-07-01

DNA methylation profile from three pairs of melanoma cell lines (WM115/W226-4 ; M4Be/M4BeS2 ; M4Be/TW12)

黑色素瘤表观遗传

肿瘤侵袭性

DNA methylation profile from three pairs of cell lines (WM115/W226-4 ; M4Be/M4BeS2 ; M4Be/TW12) with common genetic background (human) and derived in tree different organisms (human-rat-mouse) were an

NIAID Data Ecosystem90

RNA-seq of UV irradiated human epidermal melanocytes from neonatal foreskin, HEMn-DP2.. RNA-seq of UV irradiated human epidermal melanocytes from neonatal foreskin, HEMn-DP2.

黑色素瘤表观遗传

UV辐射与DNA甲基化

UVR is the principal risk factor for melanoma development. While the role of UVR in DNA mutagenesis is incontrovertible, it remains controversial what role UVR-induced mutations play in melanoma genes

NIAID Data Ecosystem50

Developmental chromatin programs determine oncogenic competence in melanoma [Cut&Run]

黑色素瘤表观遗传

发育染色质调控

We perfomed Cut&Run for ATAD2, MYC and SOX10 in 3xKO ATAD2 dox melanocytes and 3xKO dox melanocytes. We used 10'000 cells per condition and the protocol was performed as in Skene et al., 2018. We coul

NIAID Data Ecosystem20

The DNA methylation landscape of human melanoma [RNA-Seq]

黑色素瘤表观遗传

甲基化DNA生物标志物

Melanoma genomes are often characterized by large numbers of sunlight-induced mutations. However, epigenetic alterations, in the form of aberrant DNA methylation patterns, are also abundant. Using MIR

NIAID Data Ecosystem50

Genome-wide promoter methylation analysis of human melanocytes and melanoma cell lines

黑色素瘤表观遗传

启动子分析

DNA methylation profiling of human melanocytes and melanoma cell lines. Goal was to identify hypermethylated gene promoters in melanoma Genomic DNA from 4 human melanoma cell lines and normal human ep

NIAID Data Ecosystem50

CD8+ T cell responsiveness to anti-PD-1 is epigenetically regulated by Suv39h1 in melanomas

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